The C19-mineralocorticoids in hypertension.
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چکیده
منابع مشابه
The C19-mineralocorticoids in hypertension.
The excretion rates of the C19-mineralcorticoids, 16beta-hydroxy-DHEA and 16-oxo-androstenediol, were measured in subjects with low-renin essential hypertension and toxemia of pregnancy. C19-mineralocorticoid excretion in low-renin essential hypertension ranged from 70-790 microgram per day. No significant difference in 16beta-hydroxy-DHEA and 16-oxo-androstenediol excretion was found between t...
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Uninephrectomized rats drinking 1% sodium chloride were given aldosterone (Aldo, 0.75 microgram/h, subcutaneous [s.c.] infusion), deoxycorticosterone (DOC, 20 mg/wk, s.c.), corticosterone (B, 2 mg/d, s.c.), or the antiglucocorticoid-antiprogestin RU486 (2 mg/d, s.c.) for 8 wk, and hemodynamic and tissue responses were compared with a non-steroid-treated control group. Aldo and DOC markedly incr...
متن کاملMineralocorticoids: the secret of muscle reflex dysfunction in hypertension?
2 University of Nebraska Medical Center 9 Department of Cellular and Integrative Physiology 10 985850 Nebraska Medical Center 11 Omaha, NE 68198-5850 12 13 Corresponding Author: Han-Jun Wang, M.D. 14 984455 Nebraska Medical Center 15 Omaha, NE 68198-4455 16 [email protected] 17 Phone: 402-559-2493 18 Fax: 402-559-4438 19 20 Articles in PresS. Am J Physiol Heart Circ Physiol (August 19, 2017)....
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The successful use of paper chromatography for t.he separation of corticoids (2) suggested the general usefulness of this procedure for relat,ed compounds. Two procedures for t.he separation of cardiac glycosides and aglycones have been described (3, 1). Preliminary reports (5, G) and a reference (7) have been made on methods for other steroid hormones. This paper describes an effective system ...
متن کاملRelationship of 19-nor-deoxycorticosterone to other mineralocorticoids in low-renin hypertension.
A number of mineralocorticoids have been proposed as etiologic factors in low-renin hypertension. In this study, urinary free 19-nor-deoxycorticosterone (UF 19-nor-DOC) was compared to other mineralocorticoids--aldosterone, deoxycorticosterone (DOC), and 18-OH-DOC, in 11 low-renin hypertensive patients on a controlled diet in a metabolic unit. Results demonstrated that both UF 19-nor-DOC and te...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 1977
ISSN: 0009-7330,1524-4571
DOI: 10.1161/01.res.41.2.260